Deletion of the App-Runx1 region in mice models human partial monosomy 21

Partial monosomy 21 (PM21) is a rare chromosomal abnormality that is characterized by the loss of a variable segment along human chromosome 21 (Hsa21). The clinical phenotypes of this loss are heterogeneous and range from mild alterations to lethal consequences, depending on the affected region of H...

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Detalles Bibliográficos
Autores principales: Arbogast, Thomas, Raveau, Matthieu, Chevalier, Claire, Nalesso, Valérie, Dembele, Doulaye, Jacobs, Hugues, Wendling, Olivia, Roux, Michel, Duchon, Arnaud, Herault, Yann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457029/
https://www.ncbi.nlm.nih.gov/pubmed/26035870
http://dx.doi.org/10.1242/dmm.017814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457029/
https://www.ncbi.nlm.nih.gov/pubmed/26035870
http://dx.doi.org/10.1242/dmm.017814

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