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Understanding the molecular mechanisms of human microtia via a pig model of HOXA1 syndrome

Microtia is a congenital malformation of the outer ears. Although both genetic and environmental components have been implicated in microtia, the genetic causes of this innate disorder are poorly understood. Pigs have naturally occurring diseases comparable to those in humans, providing exceptional...

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Detalles Bibliográficos
Autores principales: Qiao, Ruimin, He, Yuyong, Pan, Bo, Xiao, Shijun, Zhang, Xufei, Li, Jing, Zhang, Zhiyan, Hong, Yuan, Xing, Yuyun, Ren, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457031/
https://www.ncbi.nlm.nih.gov/pubmed/26035869
http://dx.doi.org/10.1242/dmm.018291