Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with Mycobacterium tuberculosis

Cost-effective animal models that accurately reflect the pathological progression of pulmonary tuberculosis are needed to screen and evaluate novel tuberculosis drugs and drug regimens. Pulmonary disease in humans is characterized by a number of heterogeneous lesion types that reflect differences in...

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Detalles Bibliográficos
Autores principales: Irwin, Scott M., Driver, Emily, Lyon, Edward, Schrupp, Christopher, Ryan, Gavin, Gonzalez-Juarrero, Mercedes, Basaraba, Randall J., Nuermberger, Eric L., Lenaerts, Anne J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457037/
https://www.ncbi.nlm.nih.gov/pubmed/26035867
http://dx.doi.org/10.1242/dmm.019570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457037/
https://www.ncbi.nlm.nih.gov/pubmed/26035867
http://dx.doi.org/10.1242/dmm.019570

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