Systemic high-mobility group box 1 administration suppresses skin inflammation by inducing an accumulation of PDGFRα(+) mesenchymal cells from bone marrow

High-mobility group box 1 (HMGB1) mobilizes platelet-derived growth factor receptor alpha-positive (PDGFRα(+)) mesenchymal cells from bone marrow (BM) into circulation. However, whether HMGB1-induced endogenous PDGFRα(+) mesenchymal cells stimulate skin regeneration has been unclear. Here, we invest...

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Detalles Bibliográficos
Autores principales: Aikawa, Eriko, Fujita, Ryo, Kikuchi, Yasushi, Kaneda, Yasufumi, Tamai, Katsuto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457135/
https://www.ncbi.nlm.nih.gov/pubmed/26046579
http://dx.doi.org/10.1038/srep11008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457135/
https://www.ncbi.nlm.nih.gov/pubmed/26046579
http://dx.doi.org/10.1038/srep11008

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