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Probing microtubule polymerisation state at single kinetochores during metaphase chromosome motion

Kinetochores regulate the dynamics of attached microtubule bundles (kinetochore-fibres, K-fibres) to generate the forces necessary for chromosome movements in mitosis. Current models suggest that poleward-moving kinetochores are attached to depolymerising K-fibres and anti-poleward-moving kinetochor...

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Detalles Bibliográficos
Autores principales: Armond, Jonathan W., Vladimirou, Elina, Erent, Muriel, McAinsh, Andrew D., Burroughs, Nigel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457160/
https://www.ncbi.nlm.nih.gov/pubmed/25908867
http://dx.doi.org/10.1242/jcs.168682