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Restoration of Haemoglobin Level Using Hydrodynamic Gene Therapy with Erythropoietin Does Not Alleviate the Disease Progression in an Anaemic Mouse Model for TGFβ1-Induced Chronic Kidney Disease

Erythropoietin, Epo, is a 30.4 kDa glycoprotein hormone produced primarily by the fetal liver and the adult kidney. Epo exerts its haematopoietic effects by stimulating the proliferation and differentiation of erythrocytes with subsequent improved tissue oxygenation. Epo receptors are furthermore ex...

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Detalles Bibliográficos
Autores principales: Pedersen, Lea, Wogensen, Lise, Marcussen, Niels, Cecchi, Claudia R., Dalsgaard, Trine, Dagnæs-Hansen, Frederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457485/
https://www.ncbi.nlm.nih.gov/pubmed/26046536
http://dx.doi.org/10.1371/journal.pone.0128367