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Pathogen-Specific T Cell Polyfunctionality Is a Correlate of T Cell Efficacy and Immune Protection

INTRODUCTION: Understanding the factors that delineate the efficacy of T cell responses towards pathogens is crucial for our ability to develop potent therapies against infectious diseases. Multidimensional evaluation of T cell functionality at the single-cell level enables exhaustive analysis of co...

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Detalles Bibliográficos
Autores principales: Boyd, Anders, Almeida, Jorge R., Darrah, Patricia A., Sauce, Delphine, Seder, Robert A., Appay, Victor, Gorochov, Guy, Larsen, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457486/
https://www.ncbi.nlm.nih.gov/pubmed/26046523
http://dx.doi.org/10.1371/journal.pone.0128714