BRCA Mutations Increase Fertility in Families at Hereditary Breast/Ovarian Cancer Risk

BACKGROUND: Deleterious mutations in the BRCA genes are responsible for a small, but significant, proportion of breast and ovarian cancers (5 - 10 %). Proof of de novo mutations in hereditary breast/ovarian cancer (HBOC) families is rare, in contrast to founder mutations, thousands of years old, tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwiatkowski, Fabrice, Arbre, Marie, Bidet, Yannick, Laquet, Claire, Uhrhammer, Nancy, Bignon, Yves-Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457526/
https://www.ncbi.nlm.nih.gov/pubmed/26047126
http://dx.doi.org/10.1371/journal.pone.0127363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457526/
https://www.ncbi.nlm.nih.gov/pubmed/26047126
http://dx.doi.org/10.1371/journal.pone.0127363

Ejemplares similares