Hyperglycemia and Diabetes Downregulate the Functional Expression of TRPV4 Channels in Retinal Microvascular Endothelium

Retinal endothelial cell dysfunction is believed to play a key role in the etiology and pathogenesis of diabetic retinopathy. Numerous studies have shown that TRPV4 channels are critically involved in maintaining normal endothelial cell function. In the current paper, we demonstrate that TRPV4 is fu...

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Detalles Bibliográficos
Autores principales: Monaghan, Kevin, McNaughten, Jennifer, McGahon, Mary K., Kelly, Catriona, Kyle, Daniel, Yong, Phaik Har, McGeown, J. Graham, Curtis, Tim M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457535/
https://www.ncbi.nlm.nih.gov/pubmed/26047504
http://dx.doi.org/10.1371/journal.pone.0128359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457535/
https://www.ncbi.nlm.nih.gov/pubmed/26047504
http://dx.doi.org/10.1371/journal.pone.0128359

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