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Forward Programming of Cardiac Stem Cells by Homogeneous Transduction with MYOCD plus TBX5

Adult cardiac stem cells (CSCs) express many endogenous cardiogenic transcription factors including members of the Gata, Hand, Mef2, and T-box family. Unlike its DNA-binding targets, Myocardin (Myocd)—a co-activator not only for serum response factor, but also for Gata4 and Tbx5—is not expressed in...

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Detalles Bibliográficos
Autores principales: Belian, Elisa, Noseda, Michela, Abreu Paiva, Marta S., Leja, Thomas, Sampson, Robert, Schneider, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457652/
https://www.ncbi.nlm.nih.gov/pubmed/26047103
http://dx.doi.org/10.1371/journal.pone.0125384