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Loss of Homogentisate 1,2-Dioxygenase Activity in Bacillus anthracis Results in Accumulation of Protective Pigment

Melanin production is important to the pathogenicity and survival of some bacterial pathogens. In Bacillus anthracis, loss of hmgA, encoding homogentisate 1,2-dioxygenase, results in accumulation of a melanin-like pigment called pyomelanin. Pyomelanin is produced in the mutant as a byproduct of disr...

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Detalles Bibliográficos
Autores principales: Han, Hesong, Iakovenko, Liudmyla, Wilson, Adam C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457819/
https://www.ncbi.nlm.nih.gov/pubmed/26047497
http://dx.doi.org/10.1371/journal.pone.0128967