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Activated Brain Endothelial Cells Cross-Present Malaria Antigen

In the murine model of cerebral malaria caused by P. berghei ANKA (PbA), parasite-specific CD8(+) T cells directly induce pathology and have long been hypothesized to kill brain endothelial cells that have internalized PbA antigen. We previously reported that brain microvessel fragments from infecte...

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Detalles Bibliográficos
Autores principales: Howland, Shanshan W., Poh, Chek Meng, Rénia, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457820/
https://www.ncbi.nlm.nih.gov/pubmed/26046849
http://dx.doi.org/10.1371/journal.ppat.1004963