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Activated Brain Endothelial Cells Cross-Present Malaria Antigen
In the murine model of cerebral malaria caused by P. berghei ANKA (PbA), parasite-specific CD8(+) T cells directly induce pathology and have long been hypothesized to kill brain endothelial cells that have internalized PbA antigen. We previously reported that brain microvessel fragments from infecte...
Autores principales: | Howland, Shanshan W., Poh, Chek Meng, Rénia, Laurent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457820/ https://www.ncbi.nlm.nih.gov/pubmed/26046849 http://dx.doi.org/10.1371/journal.ppat.1004963 |
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