Expression of HIF-1α and Markers of Angiogenesis Are Not Significantly Different in Triple Negative Breast Cancer Compared to Other Breast Cancer Molecular Subtypes: Implications for Future Therapy

INTRODUCTION: Triple negative breast cancer lacks estrogen, progesterone and epidermal growth factor receptors rendering it refractory to available targetedtherapies. TNBC is associated with central fibrosis and necrosis, both indicators of tumor hypoxia. Hypoxia inducible factor 1α is up-regulated...

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Detalles Bibliográficos
Autores principales: Yehia, Lamis, Boulos, Fouad, Jabbour, Mark, Mahfoud, Ziyad, Fakhruddin, Najla, El-Sabban, Marwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457831/
https://www.ncbi.nlm.nih.gov/pubmed/26046764
http://dx.doi.org/10.1371/journal.pone.0129356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457831/
https://www.ncbi.nlm.nih.gov/pubmed/26046764
http://dx.doi.org/10.1371/journal.pone.0129356

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