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Avibirnavirus VP4 Protein Is a Phosphoprotein and Partially Contributes to the Cleavage of Intermediate Precursor VP4-VP3 Polyprotein

Birnavirus-encoded viral protein 4 (VP4) utilizes a Ser/Lys catalytic dyad mechanism to process polyprotein. Here three phosphorylated amino acid residues Ser538, Tyr611 and Thr674 within the VP4 protein of the infectious bursal disease virus (IBDV), a member of the genus Avibirnavirus of the family...

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Detalles Bibliográficos
Autores principales: Wang, Sanying, Hu, Boli, Si, Weiying, Jia, Lu, Zheng, Xiaojuan, Zhou, Jiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457844/
https://www.ncbi.nlm.nih.gov/pubmed/26046798
http://dx.doi.org/10.1371/journal.pone.0128828