Increased Specific Labeling of INS-1 Pancreatic Beta-Cell by Using RIP-Driven Cre Mutants with Reduced Activity

Ectopically expressed Cre recombinase in extrapancreatic tissues in RIP-Cre mice has been well documented. The objective of this study was to find a simple solution that allows for improved beta-cell specific targeting. To this end, the RIP-Cre and reporter CMV-loxP-DsRed-loxP-EGFP expression casset...

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Detalles Bibliográficos
Autores principales: Gong, Gen-cheng, Fan, Wen-zhu, Li, Di-zheng, Tian, Xiong, Chen, Shao-jun, Fu, Yu-cai, Xu, Wen-can, Wei, Chi-ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457865/
https://www.ncbi.nlm.nih.gov/pubmed/26046525
http://dx.doi.org/10.1371/journal.pone.0129092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457865/
https://www.ncbi.nlm.nih.gov/pubmed/26046525
http://dx.doi.org/10.1371/journal.pone.0129092

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