Downregulation of TNIP1 Expression Leads to Increased Proliferation of Human Keratinocytes and Severer Psoriasis-Like Conditions in an Imiquimod-Induced Mouse Model of Dermatitis

Psoriasis is a chronic, inflammatory skin disease involving both environmental and genetic factors. According to genome-wide association studies (GWAS), the TNIP1 gene, which encodes the TNF-α–induced protein 3-interacting protein 1 (TNIP1), is strongly linked to the susceptibility of psoriasis. TNI...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Yan, Heng, Song, Zhiqiang, Chen, Fangru, Wang, Huan, Niu, Jun, Shi, Xiaowei, Zhang, Dongmei, Zhang, Na, Zhai, Zhifang, Zhong, Baiyu, Cheng, Liangjin, Qian, Tian, Hao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457880/
https://www.ncbi.nlm.nih.gov/pubmed/26046540
http://dx.doi.org/10.1371/journal.pone.0127957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457880/
https://www.ncbi.nlm.nih.gov/pubmed/26046540
http://dx.doi.org/10.1371/journal.pone.0127957

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