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Malaysian endophytic fungal extracts-induced anti-inflammation in Lipopolysaccharide-activated BV-2 microglia is associated with attenuation of NO production and, IL-6 and TNF-α expression

BACKGROUND: Excessive production of inflammatory mediators such as nitric oxide (NO) and proinflammatory cytokines like tumour necrosis factor-alpha (TNF-α) from activated microglia contributes to uncontrolled inflammation in neurodegenerative diseases. This study investigated the protective role of...

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Detalles Bibliográficos
Autores principales: Harun, Azzeme, Vidyadaran, Sharmili, Lim, Siong Meng, Cole, Anthony L J, Ramasamy, Kalavathy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457982/
https://www.ncbi.nlm.nih.gov/pubmed/26047814
http://dx.doi.org/10.1186/s12906-015-0685-5