Rapid identification and recovery of ENU-induced mutations with next-generation sequencing and Paired-End Low-Error analysis

BACKGROUND: Targeting Induced Local Lesions IN Genomes (TILLING) is a reverse genetics approach to directly identify point mutations in specific genes of interest in genomic DNA from a large chemically mutagenized population. Classical TILLING processes, based on enzymatic detection of mutations in...

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Detalles Bibliográficos
Autores principales: Pan, Luyuan, Shah, Arish N, Phelps, Ian G, Doherty, Dan, Johnson, Eric A, Moens, Cecilia B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457992/
https://www.ncbi.nlm.nih.gov/pubmed/25886285
http://dx.doi.org/10.1186/s12864-015-1263-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457992/
https://www.ncbi.nlm.nih.gov/pubmed/25886285
http://dx.doi.org/10.1186/s12864-015-1263-4

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