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Copy number alterations and allelic ratio in relation to recurrence of rectal cancer

BACKGROUND: In rectal cancer, total mesorectal excision surgery combined with preoperative (chemo)radiotherapy reduces local recurrence rates but does not improve overall patient survival, a result that may be due to the harmful side effects and/or co-morbidity of preoperative treatment. New biomark...

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Detalles Bibliográficos
Autores principales: Goossens-Beumer, Inès J, Oosting, Jan, Corver, Wim E, Janssen, Marjolein JFW, Janssen, Bart, van Workum, Wilbert, Zeestraten, Eliane CM, van de Velde, Cornelis JH, Morreau, Hans, Kuppen, Peter JK, van Wezel, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458034/
https://www.ncbi.nlm.nih.gov/pubmed/26048403
http://dx.doi.org/10.1186/s12864-015-1550-0