CD8 (+) T cell response to adenovirusvaccination and subsequent suppression of tumor growth: modeling, simulation and analysis

BACKGROUND: Using immune checkpoint modulators in the clinic to increase the number and activity of cytotoxic T lymphocytes that recognize tumor antigens can prolong survival for metastatic melanoma. Yet, only a fraction of the patient population receives clinical benefit. In short, these clinical t...

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Detalles Bibliográficos
Autores principales: Wang, Qing, J Klinke, David, Wang, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458046/
https://www.ncbi.nlm.nih.gov/pubmed/26048402
http://dx.doi.org/10.1186/s12918-015-0168-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458046/
https://www.ncbi.nlm.nih.gov/pubmed/26048402
http://dx.doi.org/10.1186/s12918-015-0168-9

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