Metabolic engineering of a tyrosine-overproducing yeast platform using targeted metabolomics

BACKGROUND: L-tyrosine is a common precursor for a wide range of valuable secondary metabolites, including benzylisoquinoline alkaloids (BIAs) and many polyketides. An industrially tractable yeast strain optimized for production of L-tyrosine could serve as a platform for the development of BIA and...

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Detalles Bibliográficos
Autores principales: Gold, Nicholas D., Gowen, Christopher M., Lussier, Francois-Xavier, Cautha, Sarat C., Mahadevan, Radhakrishnan, Martin, Vincent J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458059/
https://www.ncbi.nlm.nih.gov/pubmed/26016674
http://dx.doi.org/10.1186/s12934-015-0252-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458059/
https://www.ncbi.nlm.nih.gov/pubmed/26016674
http://dx.doi.org/10.1186/s12934-015-0252-2

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