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Metabolic engineering of a tyrosine-overproducing yeast platform using targeted metabolomics
BACKGROUND: L-tyrosine is a common precursor for a wide range of valuable secondary metabolites, including benzylisoquinoline alkaloids (BIAs) and many polyketides. An industrially tractable yeast strain optimized for production of L-tyrosine could serve as a platform for the development of BIA and...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458059/ https://www.ncbi.nlm.nih.gov/pubmed/26016674 http://dx.doi.org/10.1186/s12934-015-0252-2 |