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Ghrelin prevents tumour- and cisplatin-induced muscle wasting: characterization of multiple mechanisms involved

BACKGROUND: Cachexia and muscle atrophy are common consequences of cancer and chemotherapy administration. The novel hormone ghrelin has been proposed as a treatment for this condition. Increases in food intake and direct effects on muscle proteolysis and protein synthesis are likely to mediate thes...

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Detalles Bibliográficos
Autores principales: Chen, Ji-an, Splenser, Andres, Guillory, Bobby, Luo, Jiaohua, Mendiratta, Meenal, Belinova, Blaga, Halder, Tripti, Zhang, Guohua, Li, Yi-Ping, Garcia, Jose M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458079/
https://www.ncbi.nlm.nih.gov/pubmed/26136189
http://dx.doi.org/10.1002/jcsm.12023