Ceramides in Alzheimer's Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and Aβ Accumulation

Alzheimer's disease (AD), the most common chronic and progressive neurodegenerative disorder, is characterized by extracellular deposits of amyloid β-peptides (Aβ) and intracellular deposits of hyperphosphorylated tau (phospho-tau) protein. Ceramides, the major molecules of sphingolipid metabol...

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Detalles Bibliográficos
Autores principales: Jazvinšćak Jembrek, Maja, Hof, Patrick R., Šimić, Goran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458271/
https://www.ncbi.nlm.nih.gov/pubmed/26090071
http://dx.doi.org/10.1155/2015/346783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458271/
https://www.ncbi.nlm.nih.gov/pubmed/26090071
http://dx.doi.org/10.1155/2015/346783

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