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Developing an animal model of Dupuytren’s disease by orthotopic transplantation of human fibroblasts into athymic rat
BACKGROUND: Dupuytren’s disease (DD) is a slow, progressive fibroproliferative disorder affecting the palms of the hands. The disease is characterized by the formation of collagen rich- cords which gradually shorten by the action of myofibroblasts resulting in finger contractures. It is a disease th...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458343/ https://www.ncbi.nlm.nih.gov/pubmed/26049932 http://dx.doi.org/10.1186/s12891-015-0597-z |