Preclinical Assessment of Lisdexamfetamine as an Agonist Medication Candidate for Cocaine Addiction: Effects in Rhesus Monkeys Trained to Discriminate Cocaine or to Self-Administer Cocaine in a Cocaine Versus Food Choice Procedure

BACKGROUND: Chronic amphetamine treatment decreases cocaine consumption in preclinical and human laboratory studies and in clinical trials. Lisdexamfetamine is an amphetamine prodrug in which L-lysine is conjugated to the terminal nitrogen of d-amphetamine. Prodrugs may be advantageous relative to t...

Descripción completa

Detalles Bibliográficos
Autores principales: Banks, Matthew L., Hutsell, Blake A., Blough, Bruce E., Poklis, Justin L., Negus, S. Stevens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458439/
https://www.ncbi.nlm.nih.gov/pubmed/25618405
http://dx.doi.org/10.1093/ijnp/pyv009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458439/
https://www.ncbi.nlm.nih.gov/pubmed/25618405
http://dx.doi.org/10.1093/ijnp/pyv009

Ejemplares similares