A Sweet Spot for Molecular Diagnostics: Coupling Isothermal Amplification and Strand Exchange Circuits to Glucometers

Strand exchange nucleic acid circuitry can be used to transduce isothermal nucleic acid amplification products into signals that can be readable on an off-the-shelf glucometer. Loop-mediated isothermal amplification (LAMP) is limited by the accumulation of non-specific products, but nucleic acid cir...

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Detalles Bibliográficos
Autores principales: Du, Yan, Hughes, Randall A., Bhadra, Sanchita, Jiang, Yu Sherry, Ellington, Andrew D., Li, Bingling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458886/
https://www.ncbi.nlm.nih.gov/pubmed/26050646
http://dx.doi.org/10.1038/srep11039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458886/
https://www.ncbi.nlm.nih.gov/pubmed/26050646
http://dx.doi.org/10.1038/srep11039

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