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Evaluation of Organelle Changes in Promastigotes of Unresponsive Leishmania Tropica to Meglumine Antimoniate in Comparison with Sensitive and Standard Isolates by Electron Microscopy

BACKGROUND: The control of leishmaniasis faces serious challenges because of resistance to the first-line antimonial drugs. We aimed to evaluate the differences in organelle changes of cultivated promastigotes obtained from skin lesions of sensitive and unresponsive isolates to meglumine antimoniate...

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Detalles Bibliográficos
Autores principales: Bahreini, Mitra, Bolorizadeh, Mehdi, Dabiri, Shahriar, Sharifi, Iraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458960/
https://www.ncbi.nlm.nih.gov/pubmed/26120175
http://dx.doi.org/10.4103/0019-5154.156416