Strong spurious transcription likely contributes to DNA insert bias in typical metagenomic clone libraries

BACKGROUND: Clone libraries provide researchers with a powerful resource to study nucleic acid from diverse sources. Metagenomic clone libraries in particular have aided in studies of microbial biodiversity and function, and allowed the mining of novel enzymes. Libraries are often constructed by clo...

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Detalles Bibliográficos
Autores principales: Lam, Kathy N., Charles, Trevor C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459075/
https://www.ncbi.nlm.nih.gov/pubmed/26056565
http://dx.doi.org/10.1186/s40168-015-0086-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459075/
https://www.ncbi.nlm.nih.gov/pubmed/26056565
http://dx.doi.org/10.1186/s40168-015-0086-5

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