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Strong spurious transcription likely contributes to DNA insert bias in typical metagenomic clone libraries
BACKGROUND: Clone libraries provide researchers with a powerful resource to study nucleic acid from diverse sources. Metagenomic clone libraries in particular have aided in studies of microbial biodiversity and function, and allowed the mining of novel enzymes. Libraries are often constructed by clo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459075/ https://www.ncbi.nlm.nih.gov/pubmed/26056565 http://dx.doi.org/10.1186/s40168-015-0086-5 |