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Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system

Differential mRNA expression studies implicitly assume that changes in mRNA expression have biological meaning, most likely mediated by corresponding changes in protein levels. Yet studies into mRNA-protein correspondence have shown notoriously poor correlation between mRNA and protein expression le...

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Detalles Bibliográficos
Autores principales: Koussounadis, Antonis, Langdon, Simon P., Um, In Hwa, Harrison, David J., Smith, V. Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459080/
https://www.ncbi.nlm.nih.gov/pubmed/26053859
http://dx.doi.org/10.1038/srep10775