Hedgehog Inhibitors in Rhabdomyosarcoma: A Comparison of Four Compounds and Responsiveness of Four Cell Lines

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and is divided into two major histological subgroups, i.e., embryonal (ERMS) and alveolar RMS (ARMS). RMS can show HEDGEHOG/SMOOTHENED (HH/SMO) signaling activity and several clinical trials using HH inhibitors for therapy of...

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Detalles Bibliográficos
Autores principales: Ridzewski, Rosalie, Rettberg, Diana, Dittmann, Kai, Cuvelier, Nicole, Fulda, Simone, Hahn, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459089/
https://www.ncbi.nlm.nih.gov/pubmed/26106586
http://dx.doi.org/10.3389/fonc.2015.00130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459089/
https://www.ncbi.nlm.nih.gov/pubmed/26106586
http://dx.doi.org/10.3389/fonc.2015.00130

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