STAT3-Mediated Metabolic Reprograming in Cellular Transformation and Implications for Drug Resistance

Signal transducer and activator of transcription (STAT)3 mediates the signaling downstream of cytokine and growth factor receptors, regulating the expression of target genes. It is constitutively phosphorylated on tyrosine (Y-P) in many tumors, where its transcriptional activity can induce a metabol...

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Detalles Bibliográficos
Autores principales: Poli, Valeria, Camporeale, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459099/
https://www.ncbi.nlm.nih.gov/pubmed/26106584
http://dx.doi.org/10.3389/fonc.2015.00121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459099/
https://www.ncbi.nlm.nih.gov/pubmed/26106584
http://dx.doi.org/10.3389/fonc.2015.00121

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