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STAT3-Mediated Metabolic Reprograming in Cellular Transformation and Implications for Drug Resistance
Signal transducer and activator of transcription (STAT)3 mediates the signaling downstream of cytokine and growth factor receptors, regulating the expression of target genes. It is constitutively phosphorylated on tyrosine (Y-P) in many tumors, where its transcriptional activity can induce a metabol...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459099/ https://www.ncbi.nlm.nih.gov/pubmed/26106584 http://dx.doi.org/10.3389/fonc.2015.00121 |