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Non-coding RNAs derived from an alternatively spliced REST transcript (REST-003) regulate breast cancer invasiveness

RE1-Silencing Transcription factor (REST) has a well-established role in regulating transcription of genes important for neuronal development. Its role in cancer, though significant, is less well understood. We show that REST downregulation in weakly invasive MCF-7 breast cancer cells converts them...

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Detalles Bibliográficos
Autores principales: Sook Lee, Nan, Evgrafov, Oleg V., Souaiaia, Tade, Bonyad, Adrineh, Herstein, Jennifer, Yeun Lee, Joo, Kim, Jihong, Ning, Yan, Sixto, Marcos, Weitz, Andrew C., Lenz, Heinz-Josef, Wang, Kai, Knowles, James A., Press, Michael F., Salvaterra, Paul M., Kirk Shung, K., Chow, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459148/
https://www.ncbi.nlm.nih.gov/pubmed/26053433
http://dx.doi.org/10.1038/srep11207