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Biorealistic cardiac cell culture platforms with integrated monitoring of extracellular action potentials

Current platforms for in vitro drug development utilize confluent, unorganized monolayers of heart cells to study the effect on action potential propagation. However, standard cell cultures are of limited use in cardiac research, as they do not preserve important structural and functional properties...

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Detalles Bibliográficos
Autores principales: Trantidou, Tatiana, Terracciano, Cesare M., Kontziampasis, Dimitrios, Humphrey, Eleanor J., Prodromakis, Themistoklis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459200/
https://www.ncbi.nlm.nih.gov/pubmed/26053434
http://dx.doi.org/10.1038/srep11067