MicroRNA-19a and CD22 Comprise a Feedback Loop for B Cell Response in Sepsis

BACKGROUND: MicroRNA-19a (miR-19a), an oncogenic microRNA, has been recently reported to target CD22 in B cell lymphoma cell lines, but its role in inflammatory response is unclear. CD22 is a negative regulator for BCR signaling, and we hypothesize that miR-19a regulates B cell response by targeting...

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Detalles Bibliográficos
Autores principales: Jiang, Yinan, Zhou, Hongmin, Ma, Dandan, Chen, Zhonghua Klaus, Cai, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459571/
https://www.ncbi.nlm.nih.gov/pubmed/26017478
http://dx.doi.org/10.12659/MSM.894321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459571/
https://www.ncbi.nlm.nih.gov/pubmed/26017478
http://dx.doi.org/10.12659/MSM.894321

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