Evaluation of targeting c-Src by the RGT-containing peptide as a novel antithrombotic strategy

BACKGROUND: Interaction of integrin β3 with c-Src plays critical roles in cellular signaling which is heavily implicated in platelet adhesion and aggregation, as well as in tumor cell proliferation and metastasis or in osteoclastic bone resorption. Selectively blocking integrin αIIbβ3 outside-in sig...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Jiansong, Shi, Xiaofeng, Xi, Wenda, Liu, Ping, Long, Zhangbiao, Xi, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459659/
https://www.ncbi.nlm.nih.gov/pubmed/26025329
http://dx.doi.org/10.1186/s13045-015-0159-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459659/
https://www.ncbi.nlm.nih.gov/pubmed/26025329
http://dx.doi.org/10.1186/s13045-015-0159-8

Ejemplares similares