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Optimization of sequence alignments according to the number of sequences vs. number of sites trade-off

BACKGROUND: Comparative analysis of homologous sequences enables the understanding of evolutionary patterns at the molecular level, unraveling the functional constraints that shaped the underlying genes. Bioinformatic pipelines for comparative sequence analysis typically include procedures for (i) a...

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Detalles Bibliográficos
Autores principales: Dutheil, Julien Y, Figuet, Emeric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459672/
https://www.ncbi.nlm.nih.gov/pubmed/26055961
http://dx.doi.org/10.1186/s12859-015-0619-8