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Optimization of sequence alignments according to the number of sequences vs. number of sites trade-off
BACKGROUND: Comparative analysis of homologous sequences enables the understanding of evolutionary patterns at the molecular level, unraveling the functional constraints that shaped the underlying genes. Bioinformatic pipelines for comparative sequence analysis typically include procedures for (i) a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459672/ https://www.ncbi.nlm.nih.gov/pubmed/26055961 http://dx.doi.org/10.1186/s12859-015-0619-8 |