The importance of claudin-7 palmitoylation on membrane subdomain localization and metastasis-promoting activities

BACKGROUND: Claudin-7 (cld7), a tight junction (TJ) component, is also found basolaterally and in the cytoplasm. Basolaterally located cld7 is enriched in glycolipid-enriched membrane domains (GEM), where it associates with EpCAM (EpC). The conditions driving cld7 out of TJ into GEM, which is associ...

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Detalles Bibliográficos
Autores principales: Heiler, Sarah, Mu, Wei, Zöller, Margot, Thuma, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459675/
https://www.ncbi.nlm.nih.gov/pubmed/26054340
http://dx.doi.org/10.1186/s12964-015-0105-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459675/
https://www.ncbi.nlm.nih.gov/pubmed/26054340
http://dx.doi.org/10.1186/s12964-015-0105-y

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