Comprehensive Analysis of Disease-Related Genes in Chronic Lymphocytic Leukemia by Multiplex PCR-Based Next Generation Sequencing

BACKGROUND: High resolution molecular studies have demonstrated that the clonal acquisition of gene mutations is an important mechanism that may promote rapid disease progression and drug resistance in chronic lymphocytic leukemia (CLL). Therefore, the early and sensitive detection of such mutations...

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Detalles Bibliográficos
Autores principales: Vollbrecht, Claudia, Mairinger, Fabian Dominik, Koitzsch, Ulrike, Peifer, Martin, Koenig, Katharina, Heukamp, Lukas Carl, Crispatzu, Giuliano, Wilden, Laura, Kreuzer, Karl-Anton, Hallek, Michael, Odenthal, Margarete, Herling, Carmen Diana, Buettner, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459702/
https://www.ncbi.nlm.nih.gov/pubmed/26053404
http://dx.doi.org/10.1371/journal.pone.0129544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459702/
https://www.ncbi.nlm.nih.gov/pubmed/26053404
http://dx.doi.org/10.1371/journal.pone.0129544

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