Cargando…

Comprehensive Analysis of Disease-Related Genes in Chronic Lymphocytic Leukemia by Multiplex PCR-Based Next Generation Sequencing

BACKGROUND: High resolution molecular studies have demonstrated that the clonal acquisition of gene mutations is an important mechanism that may promote rapid disease progression and drug resistance in chronic lymphocytic leukemia (CLL). Therefore, the early and sensitive detection of such mutations...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vollbrecht, Claudia, Mairinger, Fabian Dominik, Koitzsch, Ulrike, Peifer, Martin, Koenig, Katharina, Heukamp, Lukas Carl, Crispatzu, Giuliano, Wilden, Laura, Kreuzer, Karl-Anton, Hallek, Michael, Odenthal, Margarete, Herling, Carmen Diana, Buettner, Reinhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459702/ https://www.ncbi.nlm.nih.gov/pubmed/26053404 http://dx.doi.org/10.1371/journal.pone.0129544

Ejemplares similares

Mutational analysis of pulmonary tumours with neuroendocrine features using targeted massive parallel sequencing: a comparison of a neglected tumour group
por: Vollbrecht, Claudia, et al.
Publicado: (2015)

Targeted next generation sequencing of parotid gland cancer uncovers genetic heterogeneity
por: Grünewald, Inga, et al.
Publicado: (2015)

Evolution analysis of heterogeneous non-small cell lung carcinoma by ultra-deep sequencing of the mitochondrial genome
por: Amer, Wafa, et al.
Publicado: (2017)

Transcriptome analysis reveals upregulation of immune response pathways at the invasive tumour front of metastatic seminoma germ cell tumours
por: Nestler, Tim, et al.
Publicado: (2022)

Use of the GeneReader NGS System in a clinical pathology laboratory: a comparative study
por: Koitzsch, Ulrike, et al.
Publicado: (2017)

Diffusion kernel-based predictive modeling of KRAS dependency in KRAS wild type cancer cell lines
por: Ulmer, Bastian, et al.
Publicado: (2022)

Vesicular Release and Uptake of Circular LSD1-RNAs from Non-Cancer and Cancer Lung Cells
por: Galang, Joelle Noriko, et al.
Publicado: (2023)

Autophagy-Related Activation of Hepatic Stellate Cells Reduces Cellular miR-29a by Promoting Its Vesicular Secretion
por: Yu, Xiaojie, et al.
Publicado: (2022)

Dissecting Genomic Aberrations in Myeloproliferative Neoplasms by Multiplex-PCR and Next Generation Sequencing
por: Kirschner, Martin M. J., et al.
Publicado: (2015)

Multiplex PCR and Next Generation Sequencing for the Non-Invasive Detection of Bladder Cancer
por: Ward, Douglas G., et al.
Publicado: (2016)

Folic acid phenotype (FAP) is a superior biomarker predicting response to pemetrexed-based chemotherapy in malignant pleural mesothelioma
por: Mairinger, Fabian Dominik, et al.
Publicado: (2017)

E4 ubiquitin ligase promotes mitofusin turnover and mitochondrial stress response
por: Anton, Vincent, et al.
Publicado: (2023)

Comparison of Pre-Analytical FFPE Sample Preparation Methods and Their Impact on Massively Parallel Sequencing in Routine Diagnostics
por: Heydt, Carina, et al.
Publicado: (2014)

microRNAs are differentially regulated between MDM2-positive and negative malignant pleural mesothelioma
por: Walter, Robert Fred Henry, et al.
Publicado: (2016)

Notch1 Deficiency Induces Tumor Cell Accumulation Inside the Bronchiolar Lumen and Increases TAZ Expression in an Autochthonous Kras (LSL-G12V) Driven Lung Cancer Mouse Model
por: Meder, Lydia, et al.
Publicado: (2021)

Multiplex PCR−Based Next-Generation Sequencing and Global Diversity of Seoul Virus in Humans and Rats
por: Kim, Won-Keun, et al.
Publicado: (2018)

Next-generation molecular diagnostics: Leveraging digital technologies to enhance multiplexing in real-time PCR
por: Kreitmann, Louis, et al.
Publicado: (2023)

Next Generation Sequencing Based Multiplex Long-Range PCR for Routine Genotyping of Autoinflammatory Disorders
por: Guzel, Ferhat, et al.
Publicado: (2021)

Evaluation of a Prognostic Epigenetic Classification System in Chronic Lymphocytic Leukemia Patients
por: Grimm, Christina, et al.
Publicado: (2022)

Multiplex PCR of bronchoalveolar lavage fluid in children enhances the rate of pathogen detection
por: Tschiedel, Eva, et al.
Publicado: (2019)

Folic-acid metabolism and DNA-repair phenotypes differ between neuroendocrine lung tumors and associate with aggressive subtypes, therapy resistance and outcome
por: Henry Walter, Robert Fred, et al.
Publicado: (2016)

A multiplex real-time PCR assay for routine diagnosis of bacterial vaginosis
por: Kusters, J. G., et al.
Publicado: (2015)

Non-invasive prenatal diagnosis of thalassemia through multiplex PCR, target capture and next-generation sequencing
por: Yang, Xu, et al.
Publicado: (2020)

Anchored Multiplex PCR Custom Melanoma Next Generation Sequencing Panel for Analysis of Circulating Tumor DNA
por: Diefenbach, Russell J., et al.
Publicado: (2022)

Next generation multiplexing for digital PCR using a novel melt-based hairpin probe design
por: Edwards, Rebecca L., et al.
Publicado: (2023)

Fundamentals of multiplexing with digital PCR
por: Whale, Alexandra S., et al.
Publicado: (2016)

Identification of deregulation of apoptosis and cell cycle in neuroendocrine tumors of the lung via NanoString nCounter expression analysis
por: Walter, Robert Fred Henry, et al.
Publicado: (2015)

Phylogeographic analysis of hemorrhagic fever with renal syndrome patients using multiplex PCR-based next generation sequencing
por: Kim, Won-Keun, et al.
Publicado: (2016)

Confirming Multiplex RT-qPCR Use in COVID-19 with Next-Generation Sequencing: Strategies for Epidemiological Advantage
por: Carpenter, Rob E., et al.
Publicado: (2022)

Vector uncoating limits adeno-associated viral vector-mediated transduction of human dendritic cells and vector immunogenicity
por: Rossi, Axel, et al.
Publicado: (2019)

NEMO- and RelA-dependent NF-κB signaling promotes small cell lung cancer
por: Koerner, Lioba, et al.
Publicado: (2023)

Utility of Select Gene Mutation Detection in Tumors by the Idylla Rapid Multiplex PCR Platform in Comparison to Next-Generation Sequencing
por: Nkosi, Dingani, et al.
Publicado: (2022)

ACTB, CDKN1B, GAPDH, GRB2, RHOA and SDCBP Were Identified as Reference Genes in Neuroendocrine Lung Cancer via the nCounter Technology
por: Walter, Robert Fred Henry, et al.
Publicado: (2016)

Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia
por: Knittel, Gero, et al.
Publicado: (2017)

Multiplex-Ready PCR: A new method for multiplexed SSR and SNP genotyping
por: Hayden, Matthew J, et al.
Publicado: (2008)

MDM2 is an important prognostic and predictive factor for platin–pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53
por: Walter, R F H, et al.
Publicado: (2015)

SQSTM1/p62 promotes miR-198 loading into extracellular vesicles and its autophagy-related secretion
por: Yu, Xiaojie, et al.
Publicado: (2022)

A novel method for the multiplexed target enrichment of MinION next generation sequencing libraries using PCR-generated baits
por: Karamitros, Timokratis, et al.
Publicado: (2015)

Increased diagnosis of enlarged vestibular aqueduct by multiplex PCR enrichment and next‐generation sequencing of the SLC26A4 gene
por: Tian, Yongan, et al.
Publicado: (2021)

Genotyping and Molecular Diagnosis of Hepatitis A Virus in Human Clinical Samples Using Multiplex PCR-Based Next-Generation Sequencing
por: Lee, Geum-Young, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_b19shu75pghra49ur7kk7al4mv