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Computer-aided Molecular Design of Compounds Targeting Histone Modifying Enzymes

Growing evidences show that epigenetic mechanisms play crucial roles in the genesis and progression of many physiopathological processes. As a result, research in epigenetic grew at a fast pace in the last decade. In particular, the study of histone post-translational modifications encountered an ex...

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Detalles Bibliográficos
Autores principales: Andreoli, Federico, Del Rio, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459771/
https://www.ncbi.nlm.nih.gov/pubmed/26082827
http://dx.doi.org/10.1016/j.csbj.2015.04.007