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Changes in transcriptome of macrophages in atherosclerosis

Macrophages display significant phenotypic heterogeneity. Two growth factors, macrophage colony-stimulating factor and chemokine (C-X-C motif) ligand 4, drive terminal differentiation of monocytes to M0 and M4 macrophages respectively. Compared to M0 macrophages, M4 cells have a unique transcriptome...

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Detalles Bibliográficos
Autores principales: Chistiakov, Dimitry A, Bobryshev, Yuri V, Orekhov, Alexander N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459832/
https://www.ncbi.nlm.nih.gov/pubmed/25973901
http://dx.doi.org/10.1111/jcmm.12591