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Lin28a protects against cardiac ischaemia/reperfusion injury in diabetic mice through the insulin-PI3K-mTOR pathway

The insulin-PI3K-mTOR pathway exhibits a variety of cardiovascular activities including protection against I/R injury. Lin28a enhanced glucose uptake and insulin-sensitivity via insulin-PI3K-mTOR signalling pathway. However, the role of lin28a on experimental cardiac I/R injury in diabetic mice are...

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Detalles Bibliográficos
Autores principales: Zhang, Mingming, Sun, Dongdong, Li, Shuang, Pan, Xietian, Zhang, Xiaotian, Zhu, Di, Li, Congye, Zhang, Rongqing, Gao, Erhe, Wang, Haichang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459833/
https://www.ncbi.nlm.nih.gov/pubmed/25688987
http://dx.doi.org/10.1111/jcmm.12369