Cargando…
Lin28a protects against cardiac ischaemia/reperfusion injury in diabetic mice through the insulin-PI3K-mTOR pathway
The insulin-PI3K-mTOR pathway exhibits a variety of cardiovascular activities including protection against I/R injury. Lin28a enhanced glucose uptake and insulin-sensitivity via insulin-PI3K-mTOR signalling pathway. However, the role of lin28a on experimental cardiac I/R injury in diabetic mice are...
Autores principales: | Zhang, Mingming, Sun, Dongdong, Li, Shuang, Pan, Xietian, Zhang, Xiaotian, Zhu, Di, Li, Congye, Zhang, Rongqing, Gao, Erhe, Wang, Haichang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459833/ https://www.ncbi.nlm.nih.gov/pubmed/25688987 http://dx.doi.org/10.1111/jcmm.12369 |
Ejemplares similares
-
Oncostatin M (OSM) protects against cardiac ischaemia/reperfusion injury in diabetic mice by regulating apoptosis, mitochondrial biogenesis and insulin sensitivity
por: Sun, Dongdong, et al.
Publicado: (2015) -
Lin28 promoting the protective effect of PMSCs on hepatic ischaemia–reperfusion injury by regulating glucose metabolism
por: Zhou, Xi, et al.
Publicado: (2023) -
Luteolin alleviates post‐infarction cardiac dysfunction by up‐regulating autophagy through Mst1 inhibition
por: Hu, Jianqiang, et al.
Publicado: (2015) -
Danshensu alleviates cardiac ischaemia/reperfusion injury by inhibiting autophagy and apoptosis via activation of mTOR signalling
por: Fan, Guanwei, et al.
Publicado: (2016) -
miRNA‐182/Deptor/mTOR axis regulates autophagy to reduce intestinal ischaemia/reperfusion injury
por: Li, Yunsheng, et al.
Publicado: (2020)