Dedifferentiation of patient-derived glioblastoma multiforme cell lines results in a cancer stem cell-like state with mitogen-independent growth

Emerging evidence shows that glioblastoma multiforme (GBM) originates from cancer stem cells (CSCs). Characterization of CSC-specific signalling pathways would help identify new therapeutic targets and perhaps lead to the development of more efficient therapies selectively targeting CSCs. Here; we s...

Descripción completa

Detalles Bibliográficos
Autores principales: Olmez, Inan, Shen, Wangzhen, McDonald, Hayes, Ozpolat, Bulent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459842/
https://www.ncbi.nlm.nih.gov/pubmed/25787115
http://dx.doi.org/10.1111/jcmm.12479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459842/
https://www.ncbi.nlm.nih.gov/pubmed/25787115
http://dx.doi.org/10.1111/jcmm.12479

Ejemplares similares