Cargando…

Oncostatin M (OSM) protects against cardiac ischaemia/reperfusion injury in diabetic mice by regulating apoptosis, mitochondrial biogenesis and insulin sensitivity

Oncostatin M (OSM) exhibits many unique biological activities by activating Oβ receptor. However, its role in myocardial I/R injury in diabetic mice remains unknown. The involvement of OSM was assessed in diabetic mice which underwent myocardial I/R injury by OSM treatment or genetic deficiency of O...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Dongdong, Li, Shuang, Wu, Hao, Zhang, Mingming, Zhang, Xiaotian, Wei, Liping, Qin, Xing, Gao, Erhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459845/
https://www.ncbi.nlm.nih.gov/pubmed/25752217
http://dx.doi.org/10.1111/jcmm.12501